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Glenn Yank, MD is a Psychiatrist located in Tennessee.


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ShrinkTime (TM)

My aunt has been advised by her Doctor she has severe osteoporsis in her hip and he has advised her to take Actonel. I know there are many side effects to this drug. What are your thoughts on this medication? Nancy S.


According to the online reference at medlineplus,

“Bisphosphonates are a type of drug used for both the prevention and treatment of osteoporosis in postmenopausal women. The two bisphosphonates currently approved for osteoporosis — alendronate (Fosamax) and risedronate (Actonel) — prevent existing bone loss and reduce the risk of spinal and hip fractures. While side effects are generally mild, potential side effects include stomach upset and irritation of the esophagus. Because bisphosphonates are difficult to absorb, these medicines should be taken on an empty stomach. The patient should not lie down or consume food or beverages (other than water) for at least 30 minutes after taking the medicine.”

Another good review of treatment options for osteoporosis can be found at the Mayo Clinic website:

A comprehensive research review of the effectiveness and safety of this class of medicines for osteoporosis is available at:

None of the treatments for osteoporosis are without side effects, and as in all treatment situations, the benefits and risks of a particular treatment must be weighed against alternatives, including no treatment, for that individual. That said, anything that can reduce the risk of spine and hip fractures in people at risk for those fractures can be life-saving.


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